Global Mission-Driven Contract Research Organization

“Built in some of the world's most challenging research environments.
Trusted wherever research takes place.”

MISSION DRIVEN PURPOSE

Our mission driven culture creates the commitment, accountability, and partnership clients rely on throughout every stage of their program.

SCIENTIFIC & REGULATORY EXCELLENCE

Our scientific, therapeutic, and regulatory expertise helps sponsors navigate complexity and deliver high-quality clinical research across a broad range of indications.

GLOBAL EXECUTION IN COMPLEX ENVIRONMENTS

The capabilities we developed in challenging environments enable us to deliver complex studies with confidence, wherever they take place.

FLEXIBLE PARTNERSHIP

We build collaborative partnerships that provide the responsiveness, transparency, and flexibility today’s clinical development demands.

Supported More Than 600 Clinical Projects
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Finalist for Top Global CRO For The Past 2 Years

Built Over 50 Years of Clinical Research in Resource-Limited Settings
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Database of Over 1000 Research-Ready Sites
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Supported Trials in More Than 70 Countries
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Our Reach

Clinical Development Services

Tailor our services to meet your needs, from protocol design and site assessment to trial planning, implementation and management.

Who We Work With

Sponsors, biotechs, governments and regulatory agencies, other CROs, academic institutions, research sites and local communities.

Locations

We have a long history of working globally across Africa, Asia, Europe, Latin America, and North America.

Our Expertise

Therapeutic Area Expertise

Our clinical research experience spans infectious and non-communicable diseases, including respiratory, cardiometabolic, oncology, neurological, immunological, and other conditions. This broad portfolio demonstrates our versatility in supporting diverse indications, patient populations, and clinical development needs.

Specialized Expertise

Our specialist strengths include vaccine development, infectious and respiratory disease research, and more than 120 pediatric projects. We combine this expertise with proven capabilities in patient recruitment, rapid study start-up, outbreak response, and site capacity building, supported by deep local knowledge and established research networks.

Experience by Phase

From first-in-human and early-phase research to large, multi-country Phase III and IV trials, we bring experience across the clinical development lifecycle. Our teams adapt study strategies and operational approaches to meet the scientific, regulatory, and logistical requirements of each development phase.

African Footprint

For us, working in Africa means leveraging our local staff, decades of on-the-ground experience, strong stakeholder relationships, cultural competence, and a deep commitment to the region and its people.

Because of this, we’re ready to respond at a moment’s notice to implement locally adapted and staffed studies in sub-Saharan Africa that produce high-quality research. We are your partner for studies in sub-Saharan Africa.

Doctor patching the arm of a young Asian girl in a mask

About Total Trials

Our industry veterans combine therapeutic knowledge and clinical expertise to maximize impact. At Total Trials, we’re passionate problem solvers dedicated to overcoming barriers to life-saving medicines.

As forward thinkers and on-the-ground community members, we help clients achieve their research goals.

Built On Over 50 Years of Clinical Research in Resource-Limited Settings
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Supported More Than 500 Clinical Studies
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Finalist for Top Global CRO For The Past 2 Years

Database of Over 1000 Research-Ready Sites
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Supported Trials in More Than 70 Countries
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Client Reviews

Hear from our clients about their experiences working with Total Trials and how our expertise has supported their research goals

We'd like to
hear from you

Have questions or need more information? Reach out to our team—we’re here to help and eager to connect.

Get in Touch

We envision a world where advances in vaccines and medicines help all people live longer, healthier lives.