Global Mission-Driven Contract Research Organization

We manage complex clinical research in resource-limited areas

We provide end-to-end trial management, from protocol design and site selection to study execution and final analysis, ensuring faster, high-quality results for life-saving treatments and vaccines. We are dedicated to right-sized solutions including full service, single service, and FSP models.

Supported More Than 500 Clinical Studies
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Finalist for Top Global CRO For The Past 2 Years

Built Over 50 Years of Clinical Research in Resource-Limited Settings
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Database of Over 1000 Research-Ready Sites
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Supported Trials in More Than 70 Countries
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Our Reach

Full Service

Tailor our services to meet your needs, from protocol design and site assessment to trial planning, implementation and management.

Who We Work With

Sponsors, biotechs, governments and regulatory agencies, other CROs, academic institutions, research sites and local communities.

Locations

We have a long history of working globally acrossAfrica, Asia, Europe, Latin America, and North America.

Our Expertise

Infectious disease

We specialize in managing complex clinical research in resource-limited settings, addressing diseases such as malaria, HIV, and neglected tropical diseases. Our global presence allows us to rapidly respond to outbreaks, ensuring timely and effective interventions.

Oncology Clinical Research

We are experienced across a broad spectrum of solid and hematologic malignancies, specializing in early phase development. Our team can assist with the design and implementation of all phases of oncology clinical research, with expertise in endpoint selection, treatment response assessment and adjudication, and medical oversight of oncology trials.

Other Therapeutic Areas

Beyond infectious diseases and oncology, we have experience across nearly 20 therapeutic areas, including: dermatology, gastroenterology, immunology, and respiratory diseases. Our diverse expertise enables us to tailor our services to meet the unique needs of each study, ensuring rigorous and reliable results.

African Footprint

For us, working in Africa means leveraging our local staff, decades of on-the-ground experience, strong stakeholder relationships, cultural competence, and a deep commitment to the region and its people.

Because of this, we’re ready to respond at a moment’s notice to implement locally adapted and staffed studies in sub-Saharan Africa that produce high-quality research. We are your partner for studies in sub-Saharan Africa.

Doctor patching the arm of a young asain girl in a mask

About Total Trials

Our industry veterans combine therapeutic knowledge and clinical expertise to maximize impact. At Total Trials, we’re passionate problem solvers dedicated to overcoming barriers to life-saving medicines.

As forward thinkers and on-the-ground community members, we help clients achieve their research goals.

Built On Over 50 Years of Clinical Research in Resource-Limited Settings
0 +
Supported More Than 500 Clinical Studies
0 +

Finalist for Top Global CRO For The Past 2 Years

Database of Over 1000 Research-Ready Sites
0 +
Supported Trials in More Than 70 Countries
0 +

Client Reviews

Hear from our clients about their experiences working with Total Trials and how our expertise has supported their research goals

Blogs and Conferences

Blogs

FHI Clinical Rebrands to Total Trials

April 8, 2026
FHI Clinical Inc. has rebranded as TOTAL TRIALS, marking a new phase in its evolution as a global contract research organisation. The rebrand reflects expanded capabilities and global reach, while operations, services, and partnerships remain unchanged under the new name….

Blogs

Providing the Visibility Needed to Achieve Representation in Clinical Research

August 28, 2023
Fully featured CTMS and EDC can provide the visibility into enrollment trends needed to achieve representation in clinical research. Read how we use Oracle Clinical One to view and monitor participant sociodemographics and more….

Blogs

Lucas Tina, MD, MPH; VIBRI and KEMRI

July 14, 2023
Dr. Lucas Tina is affiliated with the Victoria Biomedical Research Institute (VIBRI) and Kenya Medical Research Institute (KEMRI) in Kisumu, Kenya. Dr. Tina serves as a Scientific Advisory Expert for Total Trials, and VIBRI and KEMRI are listed in Total Trials’s database of research sites….

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Our Blog

Blogs

FHI Clinical Rebrands to Total Trials

April 8, 2026
FHI Clinical Inc. has rebranded as TOTAL TRIALS, marking a new phase in its evolution as a global contract research organisation. The rebrand reflects expanded capabilities and global reach, while operations, services, and partnerships remain unchanged under the new name….

Blogs

Providing the Visibility Needed to Achieve Representation in Clinical Research

August 28, 2023
Fully featured CTMS and EDC can provide the visibility into enrollment trends needed to achieve representation in clinical research. Read how we use Oracle Clinical One to view and monitor participant sociodemographics and more….

Blogs

Lucas Tina, MD, MPH; VIBRI and KEMRI

July 14, 2023
Dr. Lucas Tina is affiliated with the Victoria Biomedical Research Institute (VIBRI) and Kenya Medical Research Institute (KEMRI) in Kisumu, Kenya. Dr. Tina serves as a Scientific Advisory Expert for Total Trials, and VIBRI and KEMRI are listed in Total Trials’s database of research sites….

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Get in Touch

We envision a world where advances in vaccines and medicines help all people live longer, healthier lives.